Intelligent Longevity Science

The constants of nature, in service of a longer human life.

Cornaro.ai unites deep bio­lo­gical meas­ure­ment with arti­fi­cial intel­li­gence to build an indus­trial plat­form for health­span exten­sion and drug-devel­op­ment decision-making.

20Years of deep-phenotyping data in aging biology
90,000Biobank samples available to us under licence
3 PBMulti-modal biological data that they are estimated to generate
2Species integrated, mouse and human, cross-validated

01

Approach

Biology sets the questions. Mathematics helps answer them.

Aging is a sys­tems prob­lem: many tis­sues, many times­cales, one tra­ject­ory. We treat it as one.

Deep biological ground truth

Two dec­ades of deep phen­o­typ­ing across genet­ic­ally diverse pop­u­la­tions, and multi-omic atlases of the tis­sues where aging does its damage.

Computation at scale

Arti­fi­cial intel­li­gence read­ing across that data at a depth and speed that no single labor­at­ory could reach unaided.

Built to translate

Find­ings are cross-val­id­ated against human cohorts from the outset, so res­ults arrive as can­did­ates for the clinic.

02

Focus areas

Four mechanisms of biology

Chosen because they are meas­ur­able, modi­fi­able, and implic­ated across more than one age-related dis­ease.

  1. 01

    NAD+ metabolism

  2. 02

    Mitochondrial function

  3. 03

    Proteostasis

  4. 04

    Metabolic and renal aging

03

Partnership

One platform, two kinds of expertise

Cornaro.ai brings deep bio­lo­gical expert­ise and sci­entific insight; Natural Constant brings AI and engin­eer­ing cap­ab­il­it­ies.

Together, they are build­ing an AI-driven indus­trial plat­form for health­span exten­sion and drug-devel­op­ment decision-making.

Work with us

We collaborate with researchers, clinicians, funders and partners who share the conviction that healthy longevity is a solvable problem.